WebApr 11, 2024 · Supplied in vials containing colistimethate sodium equal to 150 mg colistin base activity per vial. Monitoring: General: Close clinical monitoring of pediatric patients. Renal: Renal function, especially in elderly patients. Patient advice: Patients should be advised to avoid driving or using hazardous machinery during therapy. Colistimethate for Injection, USP is a sterile parenteral antibiotic product which, when reconstituted (see Reconstitution), is suitable for intramuscular or intravenous administration. Each vial contains Colistimethate sodium or pentasodium colistinmethanesulfonate (150 mg colistin base activity). … See more Typical serum and urine levels following a single 150 mg dose of Colistimethate for Injection, USP IM or IV in normal adult subjects are shown … See more Colistimethate for Injection, USP is indicated for the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli. It is particularly indicated when the infection is caused by sensitive … See more Maximum daily dose calculated from colistin base activity should not exceed 5 mg/kg/day with normal renal function. Transient … See more The use of Colistimethate for Injection, USP is contraindicated for patients with a history of sensitivity to the drug or any of its components. See more
DailyMed - COLISTIMETHATE- colistimethate sodium injection, powder…
WebColismethate Sodium LD 50 Oral Rat 5450 mg/kg Irritation/Corrosion No local irritation was reported with IV administration of reconstituted solution Sensitization No studies identified. STOT-single exposure No studies identified. STOT-repeated exposure/Repeat-dose toxicity An IM dose of 60 mg/kg/day colistimethate sodium for 30 days was lethal ... WebJan 23, 2024 · Colistimethate sodium is a surface active agent which penetrates into and disrupts the bacterial cell membrane. It has been shown to have bactericidal activity against most strains of the following microorganisms, both in vitro and in clinical infections as described in INDICATIONS AND USAGE section: Aerobic gram-negative microorganisms font variations
Colistimethate (Colistin) - GlobalRPH
WebInhale the Colistimethate mixture by aerosol nebulizer over a period of about 20 minutes, according to the directions from your doctor. Reconstituted vials of Colistimethate are … WebJul 13, 2024 · Colistimethate sodium is not indicated for infections caused by Proteus or Neisseria. Colistin sulfate (no longer commercially available in the US for oral use) has been used in infants and children for the … WebApr 11, 2024 · Common side effects of colistimethate may include: numbness or tingling in your hands, feet, mouth, or tongue; slurred speech; dizziness, spinning sensation; … font vendor itc