SpletGermano et al. demonstrated that human myxoid/round cell liposarcoma (MRCL) tumor lines treated with trabectedin have decreased levels of key inflammatory cytokines such ... Casali, P.G.; et al. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010, 70, 2235–2244. [Google Scholar] ... Splet14. sep. 2015 · Of note, the greatest increase in median PFS (5.6 months v 1.5 months with trabectedin v dacarbazine, respectively) was observed within the myxoid/round cell liposarcoma subgroup , which is consistent with the early identification of this uniquely sensitive STS subtype 25,28 and similar to a recent report of trabectedin activity in …
Liposarcoma - by Brian Schulte - The Sarcoma Letter
Splet11. dec. 2024 · Although initial trabectedin (1.2 mg/m 2) is safe and effective for patients with translocation-related sarcoma (TRS) in Japan, its efficacy in other types of soft … Splet04. jan. 2024 · In this study, trabectedin was intravenously administered in patients at the dose of 1.2 mg/m 2 over 24 h, and significantly improved progression-free survival in patients with myxoid/round-cell liposarcoma and synovial sarcoma (5.6 months versus 0.9 months). However, no significant improvement in overall survival was observed in the ... how to install yarn in linux
TAF15::NR4A3 gene fusion identifies a morphologically distinct …
Splet25. jun. 2007 · A retrospective analysis was performed on 51 patients who had advanced pretreated myxoid liposarcoma and who had begun treatment with the trabectedin between April 4, 2001 and Sept 18, 2006 in ... Splet25. maj 2024 · Trabectedin and radiotherapy in soft-tissue sarcoma (TRASTS) study: An international, prospective, phase II trial in localized myxoid liposarcoma—A collaborative Spanish (GEIS), Italian (ISG) and French (FSG) group study. Alessandro Gronchi , Nadia Hindi , Jean-Yves Blay , Andres Redondo , Roberta Sanfilippo , Carlo Morosi , ... Show More Splet30. mar. 2024 · Trabectedin was an interesting compound to combine with radiotherapy in myxoid liposarcoma for several reasons. First, trabectedin is a DNA minor groove … how to install yarn in powershell